CareerPlan

Senior Knowledge Engineer, Ontology and Data Standards (Contract)

Bay Area, CaliforniaContract$218k2026-10-08 → 2026-11-10

Core

Drive the representation of biological knowledge by governing and administering a canonical LinkML/Biolink schema and agentic curation framework to scale data profiling and validation beyond manual capacity.

Role type

Senior individual-contributor knowledge engineer (ontology and data standards)

Builds

A large canonical LinkML/Biolink schema, REST/MCP/CLI service layer, and agentic/human-in-the-loop curation framework for biological data

Domain

Biotechnology, Bioinformatics, Semantic Web, AI/LLM workflows

Deliverable

production ML models

Required skills

Ontology engineering (LinkML, Biolink, OBO Foundry, OWL, RDF, SPARQL), Python (3.12, uv, pandas, Pydantic), Agentic AI tooling (MCP, LLM workflows, RAG), Data harmonization (genomics, single-cell, screening), CI/CD for curation

Preferred skills

Protégé, ROBOT, ODK, SSSOM mapping sets, graph/relational databases, cloud storage (AWS S3)

Technologies

LinkML, Biolink, Python, FastMCP, Git, GitHub Actions, AWS S3

Responsibilities

Design and extend internal LinkML/Biolink models and ontologies; Own mapping and alignment as a discipline with recorded justification; Administer and refine the agentic curation framework and Model Context Protocol (MCP) service layer; Define mapping patterns and metadata conventions for diverse experimental modalities; Establish automated validation, LLM-assisted quality control, and CI/CD under a "curation as code" paradigm

Seniority

Senior, hands-on IC