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Principal Software Engineer

US - CA - South SF🌐 Remote💼 Full-time💰 $219,800–$219,800🗓 2026-07-08 → 2026-07-31

Core

Building cloud infrastructure, workflow platforms, and data platforms for R&D science, including Kubernetes-based execution and custom LIMS systems.

Role type

Principal Software Engineer (Infrastructure & Platform)

Builds

Cloud infrastructure, workflow execution platforms, data platforms, and AI-coding tooling for R&D teams.

Domain

Life Sciences / Bioinformatics / Cloud Infrastructure

Deliverable

production ML models | infrastructure

Required skills

Cloud architecture design, Kubernetes cluster management, Infrastructure as Code (Terraform), Python/Go programming, End-to-end product delivery, Technical leadership, Startup agility

Preferred skills

Bioinformatics computing, LIMS systems, Workflow orchestration (Nextflow, WDL, Airflow), HPC/batch-compute platforms

Technologies

AWS, Kubernetes, Python, Go, Groovy, Terraform, Helm, Nextflow, WDL, Django, React, Claude Code, Cursor

Responsibilities

Own architecture and delivery of major platform initiatives, Lead technical design reviews and decision-making, Mentor mid-level engineers, Build and improve AI-coding tooling, Partner with scientists to translate needs into platform capabilities

Seniority

Principal, hands-on IC with strategic influence

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