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CSV Engineer I

The Hearth - Columbus, OH💼 Full-time🗓 2026-05-20 → 2026-07-31

Core

Ensuring GxP computerized systems are validated in compliance with regulatory standards to support gene therapy manufacturing operations.

Role type

Junior IC CSV Engineer (GxP)

Builds

Validated computerized systems for gene therapy manufacturing

Domain

Biotechnology / Gene Therapy / GxP Compliance

Deliverable

production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work

Required skills

Computer System Validation (CSV), GAMP 5, 21 CFR Part 11, EU Annex 11, data integrity (ALCOA+), risk assessment, validation protocols (URS/FS/DS/IQ/OQ/PQ), traceability matrices, CAPA management

Preferred skills

Veeva Vault QMS, BMRAM, laboratory instrumentation validation (HPLC, UHPLC, PCR), Metasys BMS, electronic execution systems, regulatory inspection support

Technologies

Veeva Vault QMS, BMRAM, NetSuite, Waters, Agilent, Chromeleon, Softmax, Metasys, Empower, HPLC, UHPLC, PCR instruments

Responsibilities

Author, review, and execute validation deliverables for GxP computerized systems; Support CSV efforts for Veeva Vault QMS, BMRAM, and lab instruments; Perform risk assessments to determine validation approach; Manage system change control, deviations, and CAPAs; Collaborate with IT, QA, Lab Operations, and Facilities teams

Seniority

Junior, hands-on IC

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