Scientist (LS lab), IMCB (3341)
Core
Scientist conducting DNA-encoded library (DEL) screening, molecular glue discovery, and validating hits via biochemical, biophysical, and cellular assays.
Role type
Scientist (experimental/computational drug discovery)
Builds
Novel small molecules (molecular glues) and validated compound hits
Domain
Drug discovery / Chemical biology / Cancer biology
Required skills
DNA-encoded library screening, Next-generation sequencing data analysis, Cheminformatics, Recombinant protein expression, Biochemical assays, Biophysical assays, Cellular assays, Python, R, Machine learning, Statistical modelling
Preferred skills
Cancer biology, Induced-proximity therapeutics
Technologies
Python, R
Responsibilities
Conduct DEL screens, analyse sequencing data, prioritise compounds, validate selected hits using biochemical, biophysical and cellular assays
Seniority
Mid-level (PhD required)