(Senior) Scientist in Precipitation & Particle Design (temp role)
Core
Design and engineer particle attributes of peptides to enable robust, scalable, and manufacturable Active Pharmaceutical Ingredients (APIs) through crystallization and amorphous precipitation processes.
Role type
Senior IC scientist (pharmaceutical process development)
Builds
Robust precipitation and isolation processes for amorphous APIs
Domain
Pharmaceutical sciences / Chemical engineering
Required skills
amorphous precipitation principles, particle characterization, process development, experimental design, solid-state form analysis, filtration performance optimization, flowability engineering, scale-up planning, PAT tool application
Preferred skills
biomacromolecule isolation, crystallization screening, phase diagram analysis, DoE, crystal engineering, scientific modeling (G-Proms, PBM), data science (Python, R, Matlab)
Technologies
UPLC, XRD, Raman, ATR-FTIR, laser diffraction, image analysis, DSC, DVS, G-Proms, PBM
Responsibilities
Perform lab research into controlled precipitation and isolation procedures for amorphous APIs; Evaluate different precipitation and isolation technologies; Design and optimize particle engineering strategies to achieve target API characteristics; Develop mechanistic understanding of precipitation and particle formation through data-rich experimentation; Evaluate the impact of process parameters on precipitation behavior and downstream performance; Design scalable processes that consistently deliver desired API specifications
Seniority
Senior, hands-on IC
