Staff Engineer, Software
Core
Design and deploy computational analysis pipelines for single-cell VDJ sequencing data to support antibody development and immunology research.
Role type
Staff Engineer, Computational Immunology (Single-Cell Analysis)
Builds
Next-generation data processing pipelines, data infrastructure for VDJ clonotype annotation, and open-source research tools.
Domain
Computational Immunology / Bioinformatics / Single-Cell Sequencing
Deliverable
production ML models
Required skills
Single-cell VDJ sequencing data analysis, large-scale data integration, Python, SQL, machine learning frameworks (scikit-learn, TensorFlow, PyTorCh), cloud platforms (AWS, Azure), big data technologies (Spark, Databricks), statistical analysis, ETL processes, DevOps, Git
Preferred skills
Knowledge graphs, multimodal-omics data, recombinant antibody production knowledge, open-source contributions, research publications
Technologies
Python, SQL, scikit-learn, TensorFlow, PyTorch, AWS, Azure, Spark, Databricks, Git
Responsibilities
Establish methods for analyzing single-cell VDJ sequencing data, design high-throughput processing pipelines, conduct original research on affinity maturation, build data infrastructure for antibody development, annotate immunoglobin germline variation, advise on recombinant antibody production, partner with scientists to translate research into prototypes, lead open-source projects, publish and present research.
Seniority
Staff, hands-on IC with strategic impact
