Scientist II, Analytical Development
Core
Develop, optimize, and validate analytical methods for clinical-stage bacterial vaccines using modern biochemical and biophysical techniques.
Role type
Senior IC analytical development scientist
Builds
High-fidelity vaccines against bacterial diseases (e.g., pneumococcal, Group A Strep, Shigella)
Domain
Biopharmaceuticals / Vaccine Development
Required skills
HPLC/UPLC, SEC, CE, UV-Vis, ELISA, electrophoresis, plate-based assays, SDS-PAGE, icIEF, enzyme kinetics, Western Blot, PCR, method development, root-cause analysis, GLP/GMP compliance, analytical software, statistical tools
Preferred skills
Independent method optimization, troubleshooting non-routine assay issues, cross-functional collaboration, mentoring junior staff
Technologies
HPLC, UPLC, SEC, CE, UV-Vis, ELISA, SDS-PAGE, icIEF, PCR
Responsibilities
Design and execute experiments to evaluate critical method parameters; troubleshoot assay and instrument performance issues; support method transfer activities; author and revise analytical methods, SOPs, and technical reports; manage laboratory inventory and instrument maintenance; perform routine and non-routine analytical testing; ensure compliance with EHS and regulatory requirements.
Seniority
Senior, hands-on IC
