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Principal Technical Program Manager

United States💼 Full-time🗓 2026-07-15 → 2026-09-25

Core

Lead large-scale, cross-functional technical programs for Life Science and Clinical Diagnostics initiatives, driving R&D alignment, AI/ML innovation, and regulatory-compliant product delivery.

Role type

Principal Technical Program Manager

Builds

Scalable platform development roadmaps, AI/ML initiatives (computer vision, predictive diagnostics, LLM-assisted documentation), and embedded software/instrument development programs.

Domain

Life Sciences, Clinical Diagnostics, Medical Devices, Regulated Healthcare

Deliverable

production ML models | product features | infrastructure

Required skills

Cross-functional program leadership, R&D to engineering interface, AI/ML program delivery, Architecture review, SAFe/hybrid-agile program management, CI/CD and DevSecOps adoption, Executive communication, Regulatory framework knowledge (21 CFR Part 11, IEC 62304, ISO 13485), Molecular biology workflows (PCR, ddPCR, electrophoresis, flow cytometry), Embedded systems and instrument software management, Cloud-native platforms (AWS/Azure), Enterprise AI initiatives.

Preferred skills

Master's/PhD in Life Sciences or CS, PgMP/PMP/SAFe SPC certification, Laboratory environment experience (CLIA, CAP, QC), NPI governance, Platform engineering and IaC, Embedded software (C/C++, Python), Enterprise AI platforms (Claude, Azure OpenAI), Enterprise systems (SAP, Salesforce, ServiceNow, Jira, Confluence), Mentoring TPMs.

Technologies

AWS, Azure, Salesforce, SAP, ServiceNow, Jira, Confluence, C, C++, Python, Claude, Azure OpenAI

Responsibilities

Lead end-to-end delivery of multi-team programs across LSG and CDG product portfolios, Serve as primary technical program interface between R&D and engineering, Translate research innovations into scalable platform roadmaps, Drive AI/ML initiatives, Facilitate cross-functional alignment and provide executive updates, Present risk mitigation strategies, Participate in architecture reviews and guide build-versus-buy decisions, Establish and maintain SAFe/hybrid-agile practices, Define and govern program milestones and risk processes, Drive CI/CD and DevSecOps adoption, Develop executive-ready reporting and mentor program managers.

Seniority

Principal, hands-on IC with executive stakeholder management

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