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Senior Data Scientist, Agentic AI Systems

Axle Research & Technologies, Inc.🌐 Remote💼 Full-time🗓 2026-08-26 → 2026-09-26

Core

Building conversational agentic AI systems that act as an interface between patients/families and rare disease research infrastructure, capturing validated structured data to accelerate scientific discovery.

Role type

Senior individual contributor (IC) agentic AI systems engineer

Builds

Multi-turn conversational AI workflows with validated structured outputs for rare disease research

Domain

Biomedical informatics / Rare disease research

Deliverable

production ML models

Required skills

Agentic workflow engineering, structured output and tool/function calling, LLM evaluation with golden sets, end-to-end service ownership, asynchronous/concurrent Python, prompt engineering, data modeling

Preferred skills

Typed agent frameworks (Pydantic AI, LangGraph), LLM tracing/evaluation tooling, serving open-weight models, biomedical ontologies (MONDO, HPO, UMLS), rare disease domain knowledge

Technologies

Python, FastAPI, Pydantic, pytest, PostgreSQL, Kubernetes, Git, CI/CD, Langfuse, LangSmith, Arize Phoenix, Ollama, vLLM, LiteLLM

Responsibilities

Design conversation logic and confirmation steps for agentic AI; implement structured output and tool calling with Pydantic; write and test prompts for clinical reasoning; build evaluation frameworks for non-deterministic tasks; ensure responsive multi-step LLM workflows; log system decisions and reasoning; translate researcher/clinician needs into data models; contribute to scientific manuscripts and abstracts

Seniority

Senior, hands-on IC

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