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Senior Data Scientist, AI Retrieval Systems

Axle Research & Technologies, Inc.🌐 Remote💼 Full-time🗓 2026-08-26 → 2026-09-26

Core

Build the retrieval and knowledge layer for AI systems supporting rare disease research at the NIH, including semantic search, ranking, and ontology management.

Role type

Senior individual contributor machine-learning engineer (retrieval systems)

Builds

Retrieval-augmented services, knowledge layers, and interfaces for biomedical research

Domain

Biomedical informatics / Rare disease research

Deliverable

production ML models | product features

Required skills

LLM application engineering, retrieval system design, vector search, PostgreSQL, Kubernetes, Next.js/React/TypeScript, evaluation of open-ended systems, structured output

Preferred skills

Biomedical ontologies (MONDO, HPO, UMLS), entity linking, on-premises HPC deployment, open-weight model serving, rare disease domain knowledge

Technologies

Python, FastAPI, Pydantic, pytest, PostgreSQL, pgvector, Kubernetes, Helm, Next.js, React, TypeScript, Ollama, vLLM, LiteLLM

Responsibilities

Ingest and reconcile disease/phenotype ontologies into PostgreSQL; build retrieval services grounding everyday language in clinical concepts; tune keyword and vector search over biomedical corpora; build ranking and relevance layers; develop user interfaces in Next.js/React/TypeScript; deploy services to NIH on-premises Kubernetes environments; build evaluation regression suites; log system behavior and decisions; collaborate with researchers to define data models and interface design; contribute to scientific publications.

Seniority

Senior, hands-on IC

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