Senior Scientist Mass Spectrometrist
Core
Elucidate chemical structures and solve scientific questions for small molecules and peptides using high-resolution mass spectrometry tools within the pharmaceutical development continuum.
Role type
Senior Scientist Mass Spectrometrist (Structure Elucidation)
Builds
Characterization of drug candidates, degradation products, and impurities for Pfizer's portfolio.
Domain
Pharmaceutical Sciences / Synthetic Molecule Division / Mass Spectrometry
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Mass spectrometry theory and applications, structure elucidation of small molecules and peptides, organic chemistry fundamentals, HRMS systems operation (Thermo Orbitrap), MS data analysis software proficiency (Thermo Freestyle, ACD/Labs, BioPharma Finder, Protein Metrics), independent problem-solving and research
Preferred skills
Peptide/proteomics experience, knowledge of ionization sources and mass analyzers, understanding of ionization-induced fragmentation mechanisms, experience with Thermo and Bruker systems, familiarity with MS processing software (Xcalibur, DataAnalysis, Masslynx)
Responsibilities
Elucidate chemical structures using high resolution mass spectrometry, collaborate with diverse scientific disciplines (NMR, purification, analytical chemistry), provide technical and strategic input for deliverables, investigate innovative scientific approaches to MS support, utilize digital tools to enhance workflows, write technical documents, publish and present externally
Seniority
Senior, hands-on IC
