Senior Scientist Mass Spectrometrist
Core
Elucidate chemical structures and solve scientific questions for small molecules and peptides using high resolution mass spectrometry tools within the pharmaceutical development continuum.
Role type
Senior Scientist Mass Spectrometrist (Structure Elucidation)
Builds
Characterization of drug candidates, degradation products, and impurities for Pfizer's portfolio.
Domain
Pharmaceutical Sciences / Mass Spectrometry
Required skills
Mass spectrometry theory and applications, Structure elucidation of small molecules and peptides, Organic chemistry fundamentals, HRMS systems operation (Thermo Orbitrap), MS data analysis software (Thermo Freestyle, ACD/Labs, BioPharma Finder, Protein Metrics), Technical writing, Independent research and problem-solving
Preferred skills
Peptide/proteomics experience, Knowledge of ionization sources and mass analyzers, Ionization induced fragmentation mechanisms, Experience with Thermo and Bruker systems, MS processing software (Xcalibur, DataAnalysis, Masslynx)
Technologies
Thermo Orbitrap, Thermo Freestyle, ACD/Labs, BioPharma Finder, Protein Metrics, Xcalibur, DataAnalysis, Masslynx
Responsibilities
Elucidate chemical structures using high resolution mass spectrometry, Collaborate with diverse scientific disciplines (NMR, purification, analytical chemists), Provide technical and strategic input for deliverables, Investigate innovative scientific approaches to mass spectrometry support, Utilize digital tools to enhance workflows, Write technical documents and publish/present externally
Seniority
Senior, hands-on IC
