Biological Scientist
Core
Design, execute, and optimize laboratory studies in molecular biology, genome engineering, stem cell biology, and functional genomics to support NIH research programs.
Role type
Senior IC biological scientist (molecular/cellular/genomic research)
Builds
Genomic and transcriptomic data, validated cell lines, and high-throughput screening assays for translational research
Domain
Life sciences / Genomics / Stem cell biology
Required skills
Molecular cloning, CRISPR/Cas genome editing, viral vector preparation, DNA/RNA/protein isolation and quantification, cell culture (primary/stem/immortalized), stem cell differentiation, Western blotting, immunocytochemistry, immunofluorescence, high-throughput screening assay development, flow cytometry, Seahorse metabolic flux analysis, confocal microscopy, NGS/transcriptomics workflows, laboratory instrumentation maintenance, SOP development, technical reporting
Preferred skills
Prior work in federal research environment, strong scientific communication
Technologies
CRISPR/Cas, NGS, qPCR, Seahorse, flow cytometers, confocal imaging systems, cryostats, multi-electrode arrays
Responsibilities
Design and execute molecular biology experiments using gene expression analysis and functional genomics; isolate and process samples for sequencing and transcriptomics; manage cell banking activities including cryopreservation and authentication; perform protein characterization and cellular analyses; develop and validate high-throughput screening assays; collect, analyze, and interpret experimental data; maintain laboratory inventories and operate analytical equipment; prepare technical reports and scientific publications; train laboratory personnel on procedures and best practices
Seniority
Mid-level, hands-on IC