CareerPlan

Principal Scientist, Oncology Drug Discovery

Cambridge 300 Technology Square, USFull-time$116k2026-11-02 → 2026-11-10
On-site

Core

Lead basic and translational biology support for target validation, drug discovery, and early clinical development of novel small molecule cancer therapies.

Role type

Principal Scientist (Oncology Drug Discovery)

Builds

Novel small molecule cancer therapeutics

Domain

Oncology / Small molecule drug discovery

Required skills

Cancer biology, experimental design, in vitro experiments, mechanistic biology, assay development, target validation, drug discovery process

Preferred skills

Molecular oncogenesis, signaling pathways, bivalent/molecular glue modalities, genomic editing, omic methods (sequencing, transcriptomics, proteomics), statistical methods

Technologies

TCGA, CCLE, DepMap

Responsibilities

Design and execute in vitro experiments to inform asset development, champion innovative experimental techniques, guide maturation and de-risking of therapeutic concepts, build communication networks across the research unit

Seniority

Principal, hands-on IC