Principal Scientist (m/f/d) Genomic Technologies, Human Genetics and Genomics

Heidelberg - Office, DEFull-time€121k–€202k2026-10-20 → 2026-11-11

Core

Principal Scientist leading statistical genetics analysis of large-scale biobank data to identify causal gene-phenotype links, drug targets, and disease mechanisms for GSK's drug discovery pipeline.

Role type

Principal Scientist (Statistical Genetics / Genomic Technologies)

Builds

Analytical insights and interpretations of genetics/genomics data guiding portfolio decisions

Domain

Biopharmaceuticals / Human Genetics / Genomics

Deliverable

production ML models

Required skills

Statistical genetics methodology, Large-scale biobank data analysis, R or Python programming, Reproducible research practices, Causal inference modeling

Preferred skills

Cloud-based Trusted Research Environments, Machine learning, Distributed/cloud computing (SQL, PySpark, BigQuery, Docker, Nextflow), Multidisciplinary team leadership

Technologies

R, Python, SQL, PySpark, BigQuery, Docker, Nextflow

Responsibilities

Develop and implement best-in-class methods for genetic data analysis, Generate large-scale analysis outputs and visualization tools, Collaborate with translational teams to influence pipeline decisions, Stay informed on recent research in statistical genetics

Seniority

Principal, hands-on IC with strategic influence

About gsk

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.