Associate Director, QSP Modelling
Core
Lead Quantitative Systems Pharmacology (QSP) modeling to evaluate disease mechanisms, pathways, and drug candidates for prioritization and optimization in drug discovery.
Role type
Senior IC quantitative systems pharmacologist (disease lead)
Builds
Mechanistic mathematical disease models and simulations for drug discovery
Domain
Biopharma, Drug Metabolism and Pharmacokinetics (DMPK), Systems Biology
Deliverable
production ML models | product features
Required skills
QSP modeling, mathematical modeling, ODEs, parameter estimation, Python/MATLAB/SimBiology, statistical methods, disease pathophysiology
Preferred skills
Immunology, LLMs/Agentic AI, scientific machine learning (SciML), omics data integration
Technologies
MATLAB, SimBiology, Julia, Python, C/C++, Large Language Models (LLMs)
Responsibilities
Build and utilize QSP models of biological and pathophysiological processes; collaborate with biologists and clinicians to inform research programs; serve as QSP point-of-contact for project teams; develop mathematical tools to analyze causal relationships in drug-target-disease interactions; verify and validate QSP models through rigorous assessment.
Seniority
Senior, hands-on IC
