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Senior Clinical Research Physician

UK - Cambridgeshire - Addenbrookes💼 Full-time🗓 2026-08-13 → 2026-09-25

Core

Provide clinical leadership and management of clinical research physicians as Principal Investigator (PI) for early-phase and experimental medicine studies, delivering high-quality, ethically conducted trials that drive mechanistic insight and decision-making for GSK's portfolio.

Role type

Senior Clinical Research Physician (Principal Investigator)

Builds

Early-phase clinical trials, experimental medicine studies, and First-Time-In-Human (FTIH) studies

Domain

Biopharmaceuticals, Early Clinical Development, Translational Medicine

Deliverable

production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work

Required skills

Medical degree with full GMC registration, Clinical pharmacology expertise, PI/Sub-investigator experience in early-phase trials, Biomarker strategy, PK/PD, Mechanism-of-action-driven development, Team leadership and coaching, Protocol development and risk-benefit assessment, Medical safety and governance, Regulatory compliance (ICH GCP, MHRA, EMA, FDA), Adverse event management, Participant recruitment and screening, Dosing of investigational medicinal products

Preferred skills

Post-graduate qualification in clinical pharmacology, Advanced Life Support Provider qualification, Strong academic background, Experience in clinical trials quality and on-time delivery

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