Probing the methylome in cardiac remodelling in pathology and aging to discover biomarkers of health and mechanisms underlying transcriptional changes.
Core
Develop new pipelines for analyzing DNA methylation in cardiac cells to understand mechanisms of cardiac remodelling during aging and disease.
Role type
PhD researcher in epigenetics and experimental cardiology
Builds
Research projects on DNA methylation and transcriptional changes in cardiac cells
Domain
Biomedical research, epigenetics, cardiology
Deliverable
research
Required skills
NGS approaches, RNA-Seq, NGS data processing, R, Python, bioconductor packages, cell biology, mouse models/experiments
Preferred skills
single cell methods
Technologies
NGS, RNA-Seq, R, Python, bioconductor
Responsibilities
Develop new pipelines for DNA analysis in cardiac cells, determine how DNA methylation influences cardiac remodelling, collaborate with functional epigenetics and experimental cardiology laboratories, present work at conferences and lab meetings
Seniority
PhD candidate, independent researcher
