Senior Staff Bioinformatics Scientist (AI-guided protein engineering)
Core
Build computational tools and data foundations for global enzyme engineering programs, connecting screening data to AI/ML models to enable model-guided protein design.
Role type
Senior Staff Scientist (AI-guided protein engineering)
Builds
Reusable data structures, AI/ML workflows, and closed-loop design-build-test-learn systems for enzyme engineering
Domain
Biotechnology / Protein Engineering / AI for Science
Deliverable
production ML models (via careerplan.io/jobs/43547-JOB-senior-staff-bioinformatics-scientist-ai-guided-protein-engineering-at-illumina)
Required skills
Protein engineering, AI/ML for protein design, computational biology, data infrastructure design, statistical modelling, algorithm design, wet-lab screening experience, programming (Python/C++/R), protein structure modelling, molecular simulations
Preferred skills
Protein language models, generative protein design, structure prediction (AlphaFold/Rosetta), molecular dynamics, deep learning frameworks (PyTorch/TensorFlow/JAX), high-performance computing, agentic workflows
Technologies
PyTorch, TensorFlow, JAX, Rosetta, AlphaFold, RFdiffusion, Boltz, Git, UNIX
Responsibilities
Define data structures and metadata standards for high-throughput screening; Develop computational workflows linking sequence/structure/assay data to AI models; Benchmark computational and AI methods; Create reusable scripts, dashboards, and analysis pipelines; Establish closed-loop DBTL workflows; Partner with experimental scientists and automation teams
Seniority
Senior Staff, hands-on technical leadership
