Staff Scientist
Core
Lead interdisciplinary bench-to-bedside research at the National Heart, Lung, and Blood Institute (NHLBI) to investigate fundamental biological processes, cellular stress responses, and lysosomal function in human disease.
Role type
Staff Scientist (Laboratory Lead)
Builds
Translational research initiatives and therapeutic intervention sites for clinical evaluation
Domain
Biomedical research / Molecular and cellular biology
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Zebrafish model expertise (husbandry, genetic crossing, genotyping), molecular biology, cellular biology, biochemistry, advanced microscopy imaging, animal model research, laboratory leadership, mentoring
Preferred skills
Organelle cell biology (lysosomes, autophagy, intracellular trafficking), staff training experience
Technologies
Zebrafish models, advanced microscopy
Responsibilities
Combine biochemical, molecular, cellular, genetic, and quantitative approaches to investigate biological processes; Research how cells sense and adapt to stress conditions; Address alterations in mTOR, TFEB, TFE3, and lysosomal function; Identify potential sites for therapeutic intervention; Serve as laboratory lead contributing to training and mentoring; Present research at meetings and conferences; Characterize the contribution of lysosomes to physiological processes
Seniority
Senior, hands-on IC with leadership responsibilities