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Senior Research Associate , Automated Chemistry

Alewife, Cambridge, MA💼 Full-time💰 $80,000–$80,000🗓 2026-06-08 → 2026-07-31

Core

Hands-on high-throughput experimentation and automated chemical synthesis of small molecules to drive hit identification to lead optimization.

Role type

Senior Research Associate (Automated Chemistry)

Builds

Automated chemical synthesis workflows and integrated engineering solutions for small molecule discovery.

Domain

Chemistry / Materials Science / High-throughput experimentation

Deliverable

production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work

Required skills

High-throughput experimentation, automated platform operation (Chemspeed), high temp/pressure reactions, inert environment handling, small molecule synthesis, DOE protocol design, chemical handling (solvents/organics), data recording and organization, troubleshooting automation instruments

Preferred skills

Nanoparticle familiarity, high-throughput production environment experience, basic engineering skills for synthesis tools, custom script generation for automated workflows

Technologies

Chemspeed robotic workstations, gloveboxes, fume hoods, centrifuges, annealers, chemical handlers

Responsibilities

Perform chemical synthesis of small molecules in automated platforms, carry out design-build-test DOE protocols, develop and deploy integrated automation workflows, handle chemicals and air-sensitive materials, prepare reagents and samples, troubleshoot instrument/automation errors, monitor workflow performance and escalate issues, record and maintain experimental data, identify efficiency improvement opportunities, flag unusual results for review, collaborate with scientists and engineers

Seniority

Senior, hands-on IC

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