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Sr Principal/Principal Software Engineer, App

Alewife, Cambridge, MA💼 Full-time💰 $204,000–$204,000🗓 2026-06-23 → 2026-09-26

Core

Design agents, interfaces, and platform integrations enabling researchers to seamlessly collaborate with AI within a scientific discovery platform.

Role type

Sr Principal/Principal Software Engineer (Full Stack)

Builds

High-performance UIs, APIs, database schemas, and cloud infrastructure for AI-driven scientific applications.

Domain

Life Sciences / Physical Sciences / AI / Software Engineering

Deliverable

production ML models | product features | infrastructure

Required skills

Full stack development, database architecture, cloud infrastructure, system optimization, cross-functional collaboration, problem solving

Preferred skills

AI agent engineering, orchestration systems, Python for science, laboratory device integration

Technologies

React, TypeScript, Nx, TailWind, FastAPI, SQL, NoSQL, Vector DBs, AWS, Kubernetes, Terraform, GitHub Actions, Airflow, Prefect, Temporal, Dagster, Pydantic, pandas, numpy, scipy, jax, pytorch

Responsibilities

Design and build high-performance, secure UI and APIs; Develop schemas and manage diverse data systems; Drive implementation of front-end and backend services; Diagnose and optimize system bottlenecks; Leverage AWS and Kubernetes for production-grade deployments; Collaborate with ML researchers and scientists to integrate data pipelines.

Seniority

Senior, hands-on IC with architectural responsibilities

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