Principal Research Scientist II, Process Chemistry
Core
Lead the development of catalytic processes for the scalable synthesis of active pharmaceutical ingredients (APIs) and apply AI/ML tools for reaction discovery and optimization.
Role type
Principal Research Scientist II (Process Chemistry)
Builds
Scalable manufacturing processes for APIs (small molecules, peptides, antibody-drug conjugates)
Domain
Pharmaceutical manufacturing / Chemical Catalysis
Deliverable
production ML models | production ML models | physical/clinical work
Required skills
Synthetic organic chemistry, Chemical catalysis, High-throughput experimentation (HTE), AI/ML for reaction optimization, Process development, Technical leadership, Patent writing, GxP compliance
Preferred skills
Industry leadership in catalysis, High-impact publication record, People management experience
Technologies
AI/ML tools, High-throughput experimentation platforms
Responsibilities
Lead strategies for solving complex synthetic problems via chemical catalytic methods; Identify and design chemical catalysts for novel synthetic transformations; Apply CMC expertise to support business development; Leverage AI/ML and HTE to accelerate reaction screening and optimization; Lead project teams for process development and characterization; Mentor a group of scientists and define project timelines; Author technical reports, regulatory documents, and patents; Ensure adherence to GxP compliance and safety standards.
Seniority
Principal, hands-on IC with people management responsibilities
