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Principal Research Scientist II – Psychiatry Drug Discovery

Cambridge, MA, us💼 Full-time🗓 2026-08-25 → 2026-09-26

Core

Lead drug discovery programs for psychiatry indications by integrating in vitro and in vivo electrophysiological approaches to support target validation through clinical development.

Role type

Principal Research Scientist (Psychiatry Drug Discovery)

Builds

Psychiatry drug discovery programs from exploratory to late-stage discovery

Domain

Neuroscience / Psychiatry Drug Discovery

Deliverable

production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work

Required skills

Drug discovery principles, in vitro and in vivo electrophysiological approaches, neural circuits understanding, multimodal neurophysiological methodologies, translational utility assessment, research workflow development, strategic decision-making, scientific mentoring

Preferred skills

Translational frameworks, predictive approaches for functional biology data

Technologies

Electrophysiological platforms, multimodal data integration tools

Responsibilities

Establish Drug Discovery framework in Psychiatry portfolio, Contribute to the development and implementation of research workflows that integrate complex multimodal datasets, Ensure alignment of development and discovery with broader cross-functional program team goals, Support strategic decision-making in psychiatry drug discovery, Provide scientific guidance and mentoring to junior scientists and research associates

Seniority

Principal, hands-on IC with strategic oversight

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