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Senior Scientist II, Pharmaceutical Development – Thermodynamics & AI/ML Applications (all genders) (fulltime, regular)

Ludwigshafen, RP, de🌐 Remote💼 Full-time🗓 2026-08-04 → 2026-09-27

Core

Design and apply thermodynamics-based and AI/ML-enabled solutions to support pharmaceutical formulation and process development, translating physicochemical data into predictive insights for solubility, phase behavior, and stability.

Role type

Senior Scientist II, Pharmaceutical Development (Thermodynamics & AI/ML)

Builds

Predictive models, hybrid modeling approaches, and digital decision-support workflows for drug substance and drug product development.

Domain

Pharmaceutical sciences / Physical chemistry / Machine Learning

Deliverable

production ML models

Required skills

Thermodynamics, Quantum mechanics, AI/ML for scientific problems, Hybrid modeling (physics-based + data-driven), Model validation and uncertainty assessment, Data analysis of physicochemical experiments

Preferred skills

Experience with solubility, phase behavior, crystallization, supersaturation, moisture sensitivity, Excipient interactions, Process performance modeling

Technologies

Machine learning frameworks, Quantum mechanical software, Thermodynamic modeling tools

Responsibilities

Develop predictive models to guide formulation and process decisions; Apply thermodynamic and quantum mechanical principles to predict material behaviors; Build and improve models for physical stability and material compatibility; Create practical tools using hybrid physics-based and machine learning approaches; Define and execute robust model validation strategies; Convert complex datasets into actionable insights for development strategy

Seniority

Senior, hands-on IC

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