CareerPlanSign in

Senior Scientist, II Biologics & Genetic Medicine - LCMS Characterization & Bioanalysis

North Chicago, IL, us💼 Full-time🗓 2026-07-28 → 2026-09-26

Core

Develop and implement LC/MS-based bioanalysis and in vitro characterization assays for novel biologics to support stability characterization and data quality.

Role type

Senior Scientist, II Biologics & Genetic Medicine (LCMS Characterization & Bioanalysis)

Builds

Quantitative and qualitative in vitro assays for novel biologic entities

Domain

Biologics characterization, bioanalysis, and genetic medicine

Deliverable

production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work

Required skills

LC-MS methodology (protein mass spectrometry), affinity purification of biotherapeutics, in vitro stability assessment, data analysis, assay validation, team leadership

Preferred skills

Experience with QQQ, TOF, and Orbitrap platforms, knowledge of ADC in vitro characterization, AI-enabled tools for biophysical property prediction

Technologies

Protein Metrics Byos, Mass MetaSite, Empower, Chromeleon, GraphPad Prism

Responsibilities

Operate and maintain LC/MS instruments, perform affinity purification of biotherapeutics, analyze data and maintain electronic laboratory notebooks, support method development and assay optimization, evaluate novel in vitro tools and methods, serve as characterization liaison for novel biologic entities, mentor and supervise a team of 2-3 scientists

Seniority

Senior, hands-on IC with leadership responsibilities

Sourced via smartrecruiters · Listed on CareerPlan, which tracks 70,000+ jobs from 20+ sources.