Research Associate II, Bioanalytical/In Vitro ADME/DMPK
Core
Develop and validate bioanalytical methods to quantify drug candidates, metabolites, and biomarkers in biological matrices for in vitro and in vivo studies.
Role type
Senior IC bioanalytical research associate (LC-MS/MS)
Builds
Bioanalytical data supporting drug discovery PK, metabolism, and toxicology studies
Domain
Biopharmaceuticals / Drug Discovery / Bioanalysis
Required skills
LC-MS/MS method development, small molecule quantitation, metabolic identification (MetID), LC-QTOF MS/MS operation, CRO project management, stability assay design
Preferred skills
H/UPLC operation, Phoenix data management software, AB SCIEX software proficiency, non-GLP toxicology study support
Technologies
LC-MS/MS, LC-QTOF MS/MS, H/UPLC, Phoenix, AB SCIEX software
Responsibilities
Develop and qualify bioanalytical methods for drug/metabolite/biomarker analysis; Independently develop LC-MS/MS methods for in vitro and in vivo samples; Conduct in-vitro stability assays; Perform metabolic identification using LC-QTOF MS/MS; Operate, troubleshoot, and maintain LC-MS/MS systems; Manage outsourced CRO projects; Maintain scientific electronic laboratory notebooks
Seniority
Mid-Senior, hands-on IC
