Senior Scientist - Oligonucleotide Synthesis
Core
Developing innovative products for manufacturing biological drugs, specifically focusing on oligonucleotide synthesis, purification, and analytical characterization.
Role type
Senior Scientist (Oligonucleotide Synthesis & Method Development)
Builds
Automated oligonucleotide synthesis workflows, analytical methods, and robust manufacturing processes for nucleic acids.
Domain
Life Sciences / Biotechnology / Oligonucleotide Chemistry
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
phosphoramidite chemistry, solid support synthesis, automated synthesizer configuration, HPLC, LCMS, mass spectrometry, method development, verification, validation, design control, chromatography systems, UNICORN software
Preferred skills
experience in regulated R&D environments, advanced troubleshooting of chemistry and hardware issues
Technologies
HPLC, LCMS, mass spectrometer, UNICORN™ software, automated oligonucleotide synthesizers
Responsibilities
Act as subject matter expert in oligonucleotide synthesis; conduct analysis and method-related work in new product development; develop analytical methods to characterize oligonucleotides; lead and own automated oligonucleotide synthesis workflow; lead method development, optimization, verification, and validation activities; independently plan, execute, and document experimental work; present and communicate results at project meetings and conferences; act as technical advisor to customer-facing and commercial teams.
Seniority
Senior, hands-on IC