Postdoktor (2 år) inom genomik med fokus transposonerbara element i växter
Core
Investigating the role of transposable elements (TEs) as drivers of regulatory innovation in conifers (pine and spruce) compared to angiosperms (aspen), combining genomic, epigenomic, and 3D chromatin profiling with functional validation.
Role type
Postdoctoral researcher (computational genomics)
Builds
Integrated analyses linking TE-derived cis-regulatory elements to gene expression divergence; validated enhancer activity via ATAC-STARR-seq pipelines.
Domain
Plant molecular biology / Genomics / Bioinformatics
Deliverable
production ML models | research
Required skills
High-throughput sequencing data analysis (ATAC-Seq, ChIP-Seq, BS-Seq, RNA-Seq); Chromatin conformation data analysis (Hi-C, Micro-C, TADs, loops); Computational genomics (co-expression networks, comparative genomics, ML/DL for regulatory inference)
Preferred skills
Segmental duplication/WGD analysis; TE annotation and motif/footprint analysis; ATAC-STARR-seq or MPRA methods; Drought stress response research; HPC workflow development
Technologies
ATAC-Seq, ChIP-Seq, BS-Seq, EM-Seq, RNA-Seq, Hi-C, Micro-C, ATAC-STARR-seq, Python/R (implied by pipelines), Deep Learning frameworks
Responsibilities
Design and execute computational workflows for chromatin accessibility, histone modifications, methylation, and conformation analysis; Perform phylogenetic and gene duplication/family dynamics analyses; Build integrated analyses linking TE-derived elements to expression divergence; Implement pipelines for ATAC-STARR-seq data to validate enhancer activity; Curate and analyze large multi-omics datasets ensuring reproducibility; Lead manuscript writing for high-impact journals; Supervise PhD students
Seniority
Postdoctoral researcher (2 years)