Technical Development Principal Scientist, Mass Spectrometry Characterization Lead
Core
Lead mass spectrometry (MS) characterization strategy and execution for biologic therapeutics from early development to commercialization, bridging strategic leadership with hands-on laboratory expertise.
Role type
Principal Scientist, Mass Spectrometry Characterization Lead
Builds
Biologic therapeutic modalities
Domain
Biopharmaceuticals / Analytical Chemistry
Required skills
LC-MS, protein characterization, multi-attribute method (MAM) development, critical quality attributes (CQAs) identification, post-translational modifications (PTMs) quantification, regulatory filing support, process development, team mentorship
Technologies
LC-MS, MAM
Responsibilities
Lead MS characterization strategy across development stages; Design and interpret complex LC-MS analyses; Develop phase-appropriate MS methods; Identify and quantify CQAs and PTMs; Support process development milestones; Author regulatory submission sections; Collaborate with multidisciplinary teams; Mentor scientific team members
Seniority
Principal, strategic leadership with hands-on execution
