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Systems Specialist II

South San Francisco💼 Full-time💰 $91,900–$91,900🗓 2026-08-10 → 2026-09-26

Core

Operate and maintain cryoEM/cryoET instrumentation to generate high-resolution structural data for drug discovery and fundamental research.

Role type

Senior IC cryoEM/cryoET systems specialist

Builds

High-resolution cryoEM maps and in situ tomograms for structure-based drug discovery pipelines

Domain

Biophysics / Structural Biology / Drug Discovery

Deliverable

production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work

Required skills

CryoET workflows (FIB milling, tilt series), cryoEM image processing, instrumentation operation and maintenance, protocol development, cell culture support, data storage management

Preferred skills

Grid preparation, automated data collection, emerging software tools adoption

Technologies

Titan Krios, Glacios, SelectrisX Falcon4i detectors

Responsibilities

Process data to deliver high-resolution cryoEM maps; Collaborate with interdisciplinary teams to solve protein target structures; Operate and maintain cutting-edge cryoEM/cryoET instrumentation; Test and adapt emerging protocols and technologies; Train facility users across workflow stages

Seniority

Senior, hands-on IC

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