Principal Scientist | Liver Diseases (m/f/d)
Core
Lead a team of lab scientists to identify and advance novel therapeutic approaches for liver cirrhosis from target identification through candidate selection.
Role type
Principal Scientist (Drug Discovery, In Vitro Pharmacology)
Builds
Novel drug candidates for liver disease therapies
Domain
Biopharmaceuticals, Liver Disease, Drug Discovery
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Liver physiology and pathophysiology of cirrhosis, In vitro/ex vivo modeling of liver disease, Molecular/cellular/biochemical profiling, Line management and team mentoring, Cross-functional collaboration, Scientific publishing and conference presentation
Preferred skills
Knowledge of alcohol-associated liver cirrhosis, German language proficiency
Technologies
Primary cells, Organotypic cultures, Data science tools
Responsibilities
Manage an in vitro pharmacology lab and mentor lab scientists, Apply innovative in vitro and ex vivo models to identify drug candidates, Build evidence base to translate concepts from preclinical models to patients, Collaborate across disciplines including Medicinal Chemistry and Computational Innovation, Communicate complex results to stakeholders, Manage external collaborations and publish scientific papers
Seniority
Principal, hands-on IC with leadership