PhD student position
Core
Develop new approaches to treat cardiac arrhythmia using cardiac optogenetics and photopharmacology.
Role type
PhD student in cardiovascular research (cardiac electrophysiology)
Builds
New channelrhodopsins, optoGPCRs, and photopharmacological approaches for cardiac arrhythmia termination
Domain
Life Sciences / Cardiovascular research / Optogenetics
Deliverable
research
Required skills
Lab work experience, electrophysiology techniques, optogenetics, molecular biology, cell culture (HEK cells, hiPSC-derived cardiomyocytes)
Preferred skills
Patch clamp, Ca2+ imaging, multi-electrode measurements, isometric force measurements
Technologies
HEK cells, hiPSC-derived cardiomyocytes, ventricular slices
Responsibilities
Establish and characterize new approaches in cardiac optogenetics; Design, clone, and test receptor chimeras and optogenetic constructs; Learn and apply patch clamp, Ca2+ imaging, and multi-electrode measurements; Perform functional readouts of hiPSC-derived cardiomyocytes and isometric force measurements of ventricular slices