Scientist – Histology
Core
Histology Scientist supporting the advancement of novel radiopharmaceutical therapies from preclinical research through translational development and into clinical testing.
Role type
Senior hands-on histology scientist
Builds
Tissue-based assays for target validation, biodistribution, pharmacodynamic, and mechanism-of-action investigations
Domain
Oncology / Radiopharmaceuticals
Required skills
Tissue processing and embedding, Microtome sectioning, Cryosectioning, Immunohistochemistry (IHC), Immunofluorescence (IF), Automated tissue stainer operation, Antibody optimization, Antigen retrieval, Image analysis, Radioactive material handling
Preferred skills
HT or HTL (ASCP) certification, Experience with Leica systems, CRO management
Technologies
Leica systems, Cryostats, Microtomes, Automated tissue stainers, Digital pathology software
Responsibilities
Process, embed, and section FFPE and frozen tissue specimens; Design, perform, and interpret IHC and IF studies; Optimize staining protocols and antibody titration; Operate and maintain automated tissue stainers; Acquire and analyze histology data using image analysis software; Collaborate with translational and biology teams on study design and assay selection; Manage CROs for outsourced histology activities; Safely handle radioactive tissue specimens.
Seniority
Senior, hands-on IC