Principal Scientist, Process Engineering
Core
Translating lab-scale chemistry processes into safe, reliable, and scalable manufacturing operations for clinical drug supplies.
Role type
Principal Scientist, Process Engineering (Chemical Process Development)
Builds
Clinical supplies and process development for synthetic and antibody drug conjugate (ADC) drug substances
Domain
Pharmaceutical manufacturing / Chemical Engineering
Required skills
Chemical engineering fundamentals (reaction, crystallisation, distillation, extraction, filtration, drying, milling), GMP manufacturing experience, scale-up risk assessment, hazardous chemistry handling, CDMO facility assessment, batch record review, technical negotiation, cross-functional leadership
Preferred skills
Lab-based small molecule development experience, specialty chemical or petrochemical industry background, international travel readiness
Technologies
GMP environments, CDMO facilities, hazardous chemical handling systems
Responsibilities
Review batch records for hazardous chemistry campaigns to ensure safety and operational feasibility; Walk CDMO facilities (virtually or in person) to assess equipment fit and capabilities; Troubleshoot manufacturing issues to identify root causes; Present risk assessments and recommendations to leadership; Build and maintain strong relationships with global CDMO partners