Postdoctoral research associate – Modeling vascular anomalies (multiple positions) – Lawson Lab
Core
Generate and characterize human iPSC lines and zebrafish models bearing mutations associated with vascular anomalies, including endothelial cell differentiation, organ-on-a-chip phenotyping, and comparative omics studies.
Role type
Postdoctoral research associate (vascular biology)
Builds
Genetically modified iPSC lines, zebrafish models, organ-on-a-chip assays, and omics datasets
Domain
Biomedical research, developmental biology, genetics
Required skills
Genetic approaches in animal or iPSC models, molecular biology, confocal imaging, immunostaining, scRNA-seq, CRISPR, exome and whole genome sequencing
Preferred skills
Developmental biology, genetics, organ-on-a-chip models
Technologies
iPSC, zebrafish, CRISPR, scRNA-seq, organ-on-a-chip
Responsibilities
Design and implement targeting strategies for conditional activation or deletion in iPSC lines; perform phenotypic analysis of zebrafish embryos and adults; conduct serial confocal imaging and immunostaining; apply sequencing to identify second hit mutations; generate and apply new conditional alleles.
Seniority
Postdoctoral researcher