Wissenschaftliche*r Mitarbeiter*in (Postdoktorand*in) Ausschreibungs-ID: fb17-0029-wmz-2026
Core
Develop and validate optical biosensors to measure conformational dynamics of G-protein-coupled receptors (GPCRs) in living cells, and characterize GPCR responses to ligands and mechanical signals.
Role type
Postdoctoral researcher (Qualification position)
Builds
Optical biosensors and pharmacological/cell biological assays for GPCR research
Domain
Life sciences / Molecular biology / Pharmacology
Required skills
Molecular biology techniques for cloning fusion proteins, Pharmacological assays in living cells (96-well plates), GPCR/G-protein/GRK/Arrestin research experience, Data analysis and visualization, Structural modeling of GPCR-ligand interactions
Preferred skills
Development and validation of optical biosensors for living cells
Technologies
Optical biosensors, Microtiter plates (96-well), Structural modeling tools
Responsibilities
Develop and clone optical biosensors for GPCR conformational dynamics, Validate biosensors in living cells, Conduct pharmacological and cell biological assays, Analyze and visualize pharmacological datasets, Model GPCR-ligand interactions
Seniority
Postdoctoral researcher (Qualification phase)